NEURONAL CORRELATES OF INTENSIFICATION AND ACCEPTANCE OF SYMPTOMS DURING EXPOSURE THERAPY IN PATIENTS WITH OBSESSIVE-COMPULSIVE DISORDER

Neuronal correlates of intensification and acceptance of symptoms during exposure therapy in patients with obsessive-compulsive disorder

IntroductionCognitive behaviour therapy with exposure and response prevention is efficient in treating patients with obsessive-compulsive disorder (OCD).Nevertheless, it would be helpful for many patients to complement the therapeutic treatment with acceptance strategies to further increase the therapeutic benefit.The aim of the present study was t

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Explicit molecular dynamics simulation studies to discover novel natural compound analogues as Mycobacterium tuberculosis inhibitors

Tuberculosis (TB) in one of the dreadful diseases Immune Support System present globally.This is caused by Mycobacterium tuberculosis.Mycobacterium tuberculosis dethiobiotin synthetase (MtDTBS) is an essential enzyme in biotin biosynthesis and is an ideal target to design and develop novel inhibitors.In order to effectively combat this disease six

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Allometric trajectories and "stress": a quantitative approach

The term stress is an important but vague term in plant biology.We show situations in which thinking in terms of stress is profitably replaced by quantifying distance from functionally optimal scaling relationships between plant parts.These relationships include, for example, the often-cited one between leaf area and sapwood area, which presumably

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Quantifying the human wellbeing of the national wetland park: gross ecosystem product accounting of Shandong Mata Lake National Wetland Park

National wetland parks, characterized by robust ecological functions, distinctive natural landscapes, and abundant cultural resources significantly enhance human wellbeing, serve as crucial providers of ecosystem products, and exert substantial influence on local socioeconomic development and ecological conservation.There is an urgent need to carry

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